[PC] You're A What ?
Spend more than 80% of your starting character generation points on a single skill or advantage, modifiers included.
[PC] I Come From A Galaxy Far, Far Away
Play a high-TL character in a low-TL campaign
[PC] I'm Not Even Supposed To Be Here Today !
Play a character completely out of sync with the rest of the group - an everyday Joe in a group of elder gods, a cat in a group of different-era John Travolta fan posters with stats based on what art style they're done in, etc.
[GM] Haven't I Seen You Before ?
Never use anything but the unmodified example NPC packages for anyone, for any reason, for an entire campaign.
[GM] This Feels Familiar
Recreate, down to details, the setting, NPCs and rules of another game, and play it.